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Science Signaling: Video-Enhanced Protocol
In collaboration with the Journal of Visual Experiments (JoVE),
Science Signaling offers a video showing how to perform this
method for detecting protein complexes by native gel
electrophoresis. See Video and Full Text In this week's issue of Science Signaling:
ST NetWatch
- Labs and People
The Clickable Guard Cell - Description
- Rune Linding: Research Group
- Description
Glossary
- Find out what APA, Cav-1, and SRK mean in the world of cell signaling.
- New Terms | Search and Browse the Glossary
Research Articles
- Immunology
ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors - Ursula Schenk, Michela Frascoli, Michele Proietti, Robert Geffers, Elisabetta Traggiai, Jan Buer, Camillo Ricordi, Astrid M. Westendorf, and Fabio Grassi
- Sci. Signal. 4 (162), ra12. [DOI: 10.1126/scisignal.2001270]
Purinergic signaling during inflammation converts immunosuppressive CD4+ T cells into proinflammatory ones.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/ra12?etoc
Perspectives
- Neuroscience
Astrocytes Shape Axonal Signaling - Dominique Debanne and Sylvain Rama
- Sci. Signal. 4 (162), pe11. [DOI: 10.1126/scisignal.2001884]
The action potential waveform can be altered by astrocyte-mediated activation of neuronal glutamate receptors.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/pe11?etoc
Editors' Choice
- Immunology
Terms of Disengagement - Nancy R. Gough
- Sci. Signal. 4 (162), ec59. [DOI: 10.1126/scisignal.4162ec59]
To prevent destruction of self, inhibitory receptors block clustering of activating receptors and cause natural killer cells to disengage.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/ec59?etoc - Cancer
Tregs Promote Metastasis - John F. Foley
- Sci. Signal. 4 (162), ec60. [DOI: 10.1126/scisignal.4162ec60]
Receptor activator of nuclear factor  B ligand (RANKL) produced by regulatory T cells triggers the metastasis of breast cancer cells.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/ec60?etoc - Pheromone Signaling
Touch Off a Fight - Annalisa M. VanHook
- Sci. Signal. 4 (162), ec61. [DOI: 10.1126/scisignal.4162ec61]
A contact pheromone produced by females induces aggression in male squid.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/ec61?etoc - Cell Biology
Sphingolipids and Retinal Degeneration - Nancy R. Gough
- Sci. Signal. 4 (162), ec62. [DOI: 10.1126/scisignal.4162ec62]
Too much dihydrosphingosine 1-phosphate enhances degradation of photoreceptor membrane proteins and leads to retinal degeneration in flies.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/ec62?etoc - Quorum Sensing
Reaching a Quorum Isn’t Simple - Annalisa M. VanHook
- Sci. Signal. 4 (162), ec63. [DOI: 10.1126/scisignal.4162ec63]
AphA and LuxR are opposing forces in the Vibrio quorum sensing pathway.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/162/ec63?etoc Unsubscribe or edit your subscriptions for this service at: http://www.sciencemag.org/cgi/alerts/main Written requests to unsubscribe may be sent to:
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