good for you: Science Signaling Table of Contents for 22 February 2011; Vol. 4, No. 161

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Science Signaling, Volume 4, Issue 161
dated 22 February 2011, is now available at:

http://stke.sciencemag.org/content/vol4/issue161/?etoc

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Cell Biology
ER Stress Inhibits mTORC2 and Akt Signaling Through GSK-3β–Mediated Phosphorylation of Rictor: Chien-Hung Chen, Tattym Shaikenov, Timothy R. Peterson, Rakhan Aimbetov, Amangeldy K. Bissenbaev, Szu-Wei Lee, Juan Wu, Hui-Kuan Lin, and Dos D. Sarbassov; Sci. Signal. 4 (161), ra10. [DOI: 10.1126/scisignal.2001731]
Cellular stress attenuates growth factor signaling through a phosphorylation event that blocks substrate access to the kinase complex mTORC2.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ra10?etoc
Gene Expression
The Specificity of Innate Immune Responses Is Enforced by Repression of Interferon Response Elements by NF- ${kappa}$ B p50: Christine S. Cheng, Kristyn E. Feldman, James Lee, Shilpi Verma, De-Bin Huang, Kim Huynh, Mikyoung Chang, Julia V. Ponomarenko, Shao-Cong Sun, Chris A. Benedict, Gourisankar Ghosh, and Alexander Hoffmann; Sci. Signal. 4 (161), ra11. [DOI: 10.1126/scisignal.2001501]
Binding of NF- ${kappa}$ B p50 homodimers to an interferon response element restricts interferon signaling and antiviral responses to only the appropriate stimuli.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ra11?etoc

mTOR Signaling
Cofactor for Amino Acid Stimulation: Wei Wong; Sci. Signal. 4 (161), ec53. [DOI: 10.1126/scisignal.4161ec53]
Inositol polyphosphate multikinase stabilizes the mTORC1 complex and enhances amino acid–induced signaling.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ec53?etoc
Developmental Biology
Neogenin, a "Neo" Receptor for BMP: Nancy R. Gough; Sci. Signal. 4 (161), ec54. [DOI: 10.1126/scisignal.4161ec54]
Bone morphogenetic proteins (BMPs) bind the receptor neogenin to trigger pathways that inhibit BMP signaling through the transcriptional regulators Smads.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ec54?etoc
Reproductive Biology
A Helping Hand for Implantation: Annalisa M. VanHook; Sci. Signal. 4 (161), ec55. [DOI: 10.1126/scisignal.4161ec55]
Progesterone opposes estrogen-induced uterine epithelial proliferation through the transcription factor Hand2.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ec55?etoc
Cell Biology
AKTing as Individuals: Elizabeth M. Adler; Sci. Signal. 4 (161), ec56. [DOI: 10.1126/scisignal.4161ec56]
Heterogeneity in AKT activity in cell populations depends on differences in phosphoinositide 3-kinase abundance.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ec56?etoc
Plant Biology
Two Ways to Plant Symbiosis: Pamela J. Hines; Sci. Signal. 4 (161), ec57. [DOI: 10.1126/scisignal.4161ec57]
Parasponia uses a mycorrhizal signaling receptor essential for arbuscle formation to control rhizobium nodule symbiosis.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ec57?etoc
Neuroscience
Mastering Memory Maintenance: Peter R. Stern; Sci. Signal. 4 (161), ec58. [DOI: 10.1126/scisignal.4161ec58]
Tagging of cortical networks at the time of encoding is crucial for long-lasting associative memories.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/ec58?etoc

Gene Expression Science Signaling Podcast: 22 February 2011: Alexander Hoffmann and Annalisa M. VanHook; Sci. Signal. 4 (161), pc3. [DOI: 10.1126/scisignal.2001898]
A transcriptional repressor acts as a gatekeeper to restrict the innate immune response to specific stimuli.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/pc3?etoc

Cell Biology
Receptors, Signaling Networks, and Disease: Natalia Cuesta, Noa B. Martín-Cófreces, Cristina Murga, and Hisse M. van Santen; Sci. Signal. 4 (161), mr3. [DOI: 10.1126/scisignal.2001687]
This meeting in Madrid focused on signaling by immune cells and regulation of and signaling by G protein–coupled receptors.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/161/mr3?etoc

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good for you

Selasa, 22 Februari 2011

Science Signaling Table of Contents for 22 February 2011; Vol. 4, No. 161

In this week's issue of Science Signaling:

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