Selasa, 01 Februari 2011

Science Signaling Table of Contents for 1 February 2011; Vol. 4, No. 158

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Current issue cover
[About the cover]

Science Signaling, Volume 4, Issue 158
dated 1 February 2011, is now available at:

http://stke.sciencemag.org/content/vol4/issue158/?etoc


F1000  Science Signaling in F1000
 Congratulations to Science Signaling authors of papers featured in Faculty of 1000!
 Details

In this week's issue of Science Signaling:


ST NetWatch
Modeling Tools
ModuLand
Description

Hierarchical Network Organisation (HiNO)
Description

Research Articles
Metabolism
Wnt Signaling Regulates Hepatic Metabolism
Hongjun Liu, Maria M. Fergusson, J. Julie Wu, Ilsa I. Rovira, Jie Liu, Oksana Gavrilova, Teng Lu, Jianjun Bao, Donghe Han, Michael N. Sack, and Toren Finkel
Sci. Signal. 4 (158), ra6. [DOI: 10.1126/scisignal.2001249]
Nutrient deprivation triggers β-catenin–dependent expression of genes encoding gluconeogenic enzymes.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ra6?etoc

Immunology
Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling
Takumi Koshiba, Kai Yasukawa, Yusuke Yanagi, and Shun-ichiro Kawabata
Sci. Signal. 4 (158), ra7. [DOI: 10.1126/scisignal.2001147]
The contribution of mitochondria to antiviral immune responses extends beyond their role as a platform for antiviral signaling molecules.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ra7?etoc


Perspectives
Immunology
To Be or Not to Be a Treg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms
Aras Toker and Jochen Huehn
Sci. Signal. 4 (158), pe4. [DOI: 10.1126/scisignal.2001783]
Differentiation of natural regulatory T cells is restricted by the SUMO ligase PIAS1.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/pe4?etoc


Editors' Choice
Circadian Rhythms
Free from Transcription
John F. Foley
Sci. Signal. 4 (158), ec29. [DOI: 10.1126/scisignal.4158ec29]
Circadian rhythms in humans and algae can occur without the need for transcription-translation feedback control.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ec29?etoc

Membranes
Flipping for Opsin
Elizabeth M. Adler
Sci. Signal. 4 (158), ec30. [DOI: 10.1126/scisignal.4158ec30]
The G protein–coupled receptor opsin acts as a phospholipid flippase.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ec30?etoc

Immunology
Are You Experienced?
Wei Wong
Sci. Signal. 4 (158), ec31. [DOI: 10.1126/scisignal.4158ec31]
In naïve and experienced human T cells, activation of the TCR elicits different signaling pathways.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ec31?etoc

Cancer
MALT Lymphomagenesis Revisited
Kristen L. Mueller
Sci. Signal. 4 (158), ec32. [DOI: 10.1126/scisignal.4158ec32]
An oncogenic fusion protein promotes lymphomagenesis by activating a noncanonical signaling pathway.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ec32?etoc

Autophagy
So Hungry I Could Eat Myself
L. Bryan Ray
Sci. Signal. 4 (158), ec33. [DOI: 10.1126/scisignal.4158ec33]
A protein kinase links energy stores to control of autophagy.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ec33?etoc

Parasitology
Parasite Replication Trigger
Stella M. Hurtley
Sci. Signal. 4 (158), ec34. [DOI: 10.1126/scisignal.4158ec34]
Membrane proteins govern a change from invasion to replication of an intracellular parasite.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/158/ec34?etoc

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Watch Previously Recorded Webinars from AAAS/Science

View our collection of over 25 webinars on www.sciencemag.org/webinar
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Featuring presentations from world renowned experts on a broad range
of topics, including Noncoding RNAs, Apoptosis, qPCR, Next-Gen
Sequencing, and Stem Cell Research, the webinars are a tremendous
learning tool that include previously recorded question and answer
segments.
Watch Science Webinars today at www.sciencemag.org/webinar.

 



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